Author/Authors :
Guo، نويسنده , , Zhimou and Liu، نويسنده , , Yanfang and Xu، نويسنده , , Junyan and Xu، نويسنده , , Qing and Xue، نويسنده , , Xingya and Zhang، نويسنده , , Feifang and Ke، نويسنده , , Yanxiong and Liang، نويسنده , , Xinmiao and Lei، نويسنده , , Aiwen، نويسنده ,
Abstract :
Oligo(ethylene glycol) (OEG) covalently bonded silica was prepared by using click chemistry and employed as a stationary phase for reversed-phase high-performance liquid chromatography. The column efficiency and effect of organic modifier content on retention were investigated. The separation selectivity was also studied with phenyl compounds and an actual sample of natural products. The results indicated that the stationary phase possessed good separation efficiency and separation selectivity in RP-HPLC mode. Moreover, the stationary phase showed good complementary separation selectivity to the C18 stationary phase. The OEG stationary phase had “clustering” function for “homologous component” in the separation of natural products.
Keywords :
Oligo(ethylene glycol) , stationary phase , High-performance liquid chromatography , click chemistry
