• Title of article

    Application of the “VARICOL” process to the separation of the isomers of the SB-553261 racemate

  • Author/Authors

    Giovanni and Ludemann-Hombourger، نويسنده , , O. and Pigorini، نويسنده , , G. and Nicoud، نويسنده , , R.M. and Ross، نويسنده , , D.S. and Terfloth، نويسنده , , G.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2002
  • Pages
    10
  • From page
    59
  • To page
    68
  • Abstract
    A new continuous chromatographic process (VARICOL) has been presented recently. The basic principle of the new VARICOL process consists of an asynchronous shift of the inlet/outlet lines in a multi-column system on a recycle loop. This process has been used to perform the separation of the optical isomers of the SB-553261 racemate. In this paper, we illustrate that for this specific separation, the VARICOL process is more efficient than the well-known SMB process.
  • Keywords
    SB-553261
  • Journal title
    Journal of Chromatography A
  • Serial Year
    2002
  • Journal title
    Journal of Chromatography A
  • Record number

    1517148