Author/Authors :
Giovanni and Ludemann-Hombourger، نويسنده , , O. and Pigorini، نويسنده , , G. and Nicoud، نويسنده , , R.M. and Ross، نويسنده , , D.S. and Terfloth، نويسنده , , G.، نويسنده ,
Abstract :
A new continuous chromatographic process (VARICOL) has been presented recently. The basic principle of the new VARICOL process consists of an asynchronous shift of the inlet/outlet lines in a multi-column system on a recycle loop. This process has been used to perform the separation of the optical isomers of the SB-553261 racemate. In this paper, we illustrate that for this specific separation, the VARICOL process is more efficient than the well-known SMB process.
