Author/Authors :
Yvan and Visky، نويسنده , , D?ra and Vander Heyden، نويسنده , , Yvan and Iv?nyi، نويسنده , , T??mea and Baten، نويسنده , , Peggy and De Beer، نويسنده , , Jacques and Kov?cs، نويسنده , , Zsuzsanna and Nosz?l، نويسنده , , Béla and Roets، نويسنده , , Eugène and Massart، نويسنده , , Désiré L. and Hoogmartens، نويسنده , , Jos، نويسنده ,
Abstract :
The European Pharmacopoeia (Ph. Eur.) or other official compendia give only a general description of the stationary phase in the description of a liquid chromatographic method. Therefore the selection of a column giving suitable selectivity presents difficulties. Earlier, a test procedure was proposed that allows measurement of a number of parameters which are reported to be representative for stationary phase characteristics. This paper describes how the test procedure was applied on 69 RP-LC C18 columns. Chromatographic parameters obtained as test results were evaluated, and their repeatability, reproducibility and correlation were examined.
