Transportable frontal chromatographic unit for decontamination purposes based on the twin column concept

The design and operation of a separation unit based on frontal chromatography is described. The important feature of the design is the array column → detector → column which allows process monitoring below the detection limits of the monitor. By using “fraternal twin columns” an in-process calibration of the detector is achieved reducing the waste production. The design contains provisions for on-line destructive and non-destructive monitoring. Tests of the unit prove its versatility with respect to decontamination processes. Due to its compactness, the unit is transportable, if not portable, and the module construction allows easy posting and set-up in areas with restricted access. The unit is capable of processing up to 5 m3 solution per year depending on the chemical system used.