Title of article :
Physicochemical properties of enhanced-fluidity liquid solvents
Author/Authors :
Olesik، نويسنده , , Susan V، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2004
Abstract :
Enhanced fluidity (EF) liquid mixtures are advantageous as mobile phases for the separation of moderate to polar compounds in liquid chromatography (reversed-phase, normal, size exclusion, size exclusion, and chiral separations). The low viscosities and high diffusivities of EF mixtures allow highly efficient separations to be achieved in a small amount of time. The best use of enhanced-fluidity liquids is only possible when their physicochemical properties are known. Herein, the techniques used to measure the physicochemical properties (phase diagram, diffusivity, solvent strength and pH) of EF liquids are described. For each technique, the experiment design and the care necessary to insure the quality of the collected data are described. Finally, the impact of the measured physicochemical properties on the chromatography is also highlighted.
Keywords :
reviews , Enhance-fluidity liquid solvents , Mobile phase composition
Journal title :
Journal of Chromatography A
Journal title :
Journal of Chromatography A