Development of a total analytical system by interfacing membrane extraction, pervaporation and high-performance liquid chromatography

This paper discusses the interfacing of continuous membrane extraction, pervaporation and on-line HPLC–UV detection into a total analytical system (TAS). Organics from a water sample were extracted into an organic solvent, and then concentrated via pervaporation prior to HPLC–UV detection. Factors affecting the system performance were studied. With optimized experimental parameters enrichment factors as high as 192 were obtained, the method detection limits were at low ng/mL levels, and the precisions were better than 5%.