Metabolome analysis by capillary electrophoresis–mass spectrometry

Capillary electrophoresis (CE)–mass spectrometry (MS), as an analytical platform, has made significant contributions in advancing metabolomics research, if still limited up to this time. This review, covering reports published between 1998 and 2006, describes how CE–MS has been used thus far in this field, with the majority of the works dealing with targeted metabolite analyses and only a small fraction using it in the comprehensive context. It also discusses how some of the key features of CE–MS were exploited in selected metabolomic applications.