• Title of article

    Erratum to “High-performance liquid-chromatographic determination of 5-aminosalicylic acid and its metabolites in blood plasma” [J. Chromatogr. A 1119 (2006) 299–308]

  • Author/Authors

    Nobilis، نويسنده , , M. and Vyb?ralov?، نويسنده , , Z. and Sl?dkov?، نويسنده , , Douglas K. and Lisa Price، نويسنده , , M. and Hol?apek، نويسنده , , M. and Kv?tina، نويسنده , , J.، نويسنده ,

  • Issue Information
    روزنامه با شماره پیاپی سال 2006
  • Pages
    1
  • From page
    248
  • To page
    248
  • Abstract
    Oleuropein and other healthy olive biophenols (OBPs) such as verbacoside, apigenin-7-glucoside and luteolin-7-glucoside have been extracted from olive leaves by using superheated liquids and a static–dynamic approach. Multivariate methodology has been used to carry out a detailed optimisation of the extraction. Under the optimal working conditions, complete removal without degradation of the target analytes was achieved in 13 min. The extract was injected into a chromatograph–photodiode array detector assembly for individual separation–quantification. The proposed approach – which provides more concentrated extracts than previous alternatives – is very useful to study matrix–extractant analytes partition. In addition, the efficacy of superheated liquids to extract OBPs, the simplicity of the experimental setup, its easy automation and low acquisition and maintenance costs make the industrial implementation of the proposed method advisable.
  • Keywords
    Mesalazine (5-aminosalicylic acid , 5-ASA) , N-acyl derivatives of 5-ASA , HPLC with UV photodiode-array , fluorescence and mass-spectrometric detections , Pharmacokinetics
  • Journal title
    Journal of Chromatography A
  • Serial Year
    2006
  • Journal title
    Journal of Chromatography A
  • Record number

    1522912