Metal tubing/frit with a sintered frit of silica particles and a chromatography column with such tubing/frits

This study is about the metal tubing/frit prepared by treating a powdered silica with a strong base, drying it, scrubbing it into powders, putting it in the tip of metal tubing at a proper depth, and sintering the powders to form a durable sintered frit. This study is also about a liquid chromatographic column prepared by installing the metal tubing/frit at the column inlet and outlet unions and by placing the column main body tubing packed with a stationary phase between the two unions. The metal tubing/frit made according to the description is easily replaced and fixed without disassembling the column when it is necessary. The column of this design could be a cheap substitute for the conventional microcolumn.