Title of article :
Impurity analysis of 1,4-dioxane in nonionic surfactants and cosmetics using headspace solid-phase microextraction coupled with gas chromatography and gas chromatography–mass spectrometry
Author/Authors :
Fuh، نويسنده , , C. Bor and Lai، نويسنده , , M. and Tsai، نويسنده , , H.Y. and Chang، نويسنده , , C.M.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Pages :
5
From page :
141
To page :
145
Abstract :
1,4-Dioxane impurity in nonionic surfactants and cosmetics were analyzed using solid-phase microextraction (SPME) coupled with gas chromatography (GC) and gas chromatography–mass spectrometry (GC–MS). Experimental results show that there is no significant difference using SPME–GC and SPME–GC–MS for analysis of 1,4-dioxane in three types of nonionic surfactants at the 95% confidence level. The relative standard deviation (R.S.D.) values of each analytical method were smaller than 3%. The amount of 1,4-dioxane was found to vary from 11.6 ± 0.3 ppm to 73.5 ± 0.5 ppm in 30% of nonionic surfactants from manufacturers in Taiwan. These methods were linear over the studied range of 3–150 ppm with correlation coefficients higher than 0.995. The recoveries of 1,4-dioxane for these nonionic surfactants following SPME were all higher than 96 ± 1% (n = 3). The detection limits of 1,4-dioxane for these nonionic surfactants following SPME were from 0.06 ppm to 0.51 ppm. The experimentally determined level of 1,4-dioxane in cosmetics from manufacturers in Taiwan varied from 4.2 ± 0.1 ppm to 41.1 ± 0.6 ppm in 22% of daily used cosmetics following SPME coupled with GC and GC–MS. Conventional solvent extraction takes around 1 h for extraction and reconcentration but SPME takes only around 10 min. SPME provides better analyses of 1,4-dioxane in nonionic surfactants and cosmetics than conventional solvent extraction and head space pretreatments in term of simplicity, speed, precision, detection limit, and solvent consumption.
Keywords :
1 , 4-dioxane , Solid phase microextraction , Nonionic surfactants
Journal title :
Journal of Chromatography A
Serial Year :
2005
Journal title :
Journal of Chromatography A
Record number :
1523928
Link To Document :
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