Title of article :
New multiresidue analytical method dedicated to trace level measurement of brominated flame retardants in human biological matrices
Author/Authors :
Cariou، نويسنده , , Ronan and Antignac، نويسنده , , Jean-Philippe and Marchand، نويسنده , , Philippe and Berrebi، نويسنده , , Alain and Zalko، نويسنده , , Daniel and André، نويسنده , , François and Le Bizec، نويسنده , , Bruno، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
A new method has been developed for the multi-residue measurement of the main brominated flame retardants (α- and γ-hexabromocyclododecane (HBCD), tetrabromobisphenol A (TBBP-A) and polybrominated diphenyl ethers including decabromodiphenyl ether) in human biological matrices (serum, adipose tissue and breast milk). The proposed sample preparation procedure focused on reduced solvent and consumable consumption and associated procedural contamination, as well as reduced sample size. This protocol was fully validated and was proved to be suitable for identification of brominated flame retardant residues at ultra-trace level, as attested by preliminary results on real samples.
Keywords :
Tetrabromobisphenol A , Sample preparation , HRMS , Serum adipose tissue , milk , Polybrominated diphenylether , Hexabromocyclododecane
Journal title :
Journal of Chromatography A
Journal title :
Journal of Chromatography A