Title of article
Faster axial band dispersion in a monolithic silica column than in a particle-packed column
Author/Authors
Kobayashi، نويسنده , , Hiroshi and Tokuda، نويسنده , , Daisuke and Ichimaru، نويسنده , , Jun and Ikegami، نويسنده , , Tohru and Miyabe، نويسنده , , Kanji and Tanaka، نويسنده , , Nobuo، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
8
From page
2
To page
9
Abstract
The contribution of molecular diffusion to peak broadening was studied in a reversed-phase HPLC system, consisting of a monolithic silica C18 column and methanol–water mobile phase. Study on the band broadening effect of holding a solute in a column or elution at very low linear velocity of mobile phase allowed facile determination of the contribution of the molecular diffusion term. Less obstruction against molecular diffusion, or the faster axial band dispersion in a monolithic silica column than in a particle-packed column, was found both in mobile phase and in stationary phase.
Keywords
Molecular diffusion , Band dispersion , Monolithic silica column
Journal title
Journal of Chromatography A
Serial Year
2006
Journal title
Journal of Chromatography A
Record number
1524801
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