Title of article :
Non-coding DNA Can Regulate Gene Transcription by its Base Pairʹs Distribution
Author/Authors :
Sandler، نويسنده , , U. and Wyler، نويسنده , , A.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 1998
Abstract :
In this paper we show that the gene transcription velocity can depend exponentially on the first moments of the base pair distribution in DNA. As the major fraction of the DNA of eucaryotes consists of non-coding sequences of base pairs and these determine the statistical characteristics of the base pairʹs ordering, non-coding DNA plays an important role in the functioning of the genetic apparatus. In particular, it enables a new independent mechanism for the gradual regulation of gene expression in eucaryotes.
Journal title :
Journal of Theoretical Biology
Journal title :
Journal of Theoretical Biology