Title of article :
A stochastic model in tumor growth
Author/Authors :
Albano، نويسنده , , G. and Giorno، نويسنده , , V.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
A stochastic model of solid tumor growth based on deterministic Gompertz law is presented. Tumor cells evolution is described by a one-dimensional diffusion process limited by two absorbing boundaries representing healing threshold and patient death (carrying capacity), respectively. Via a numerical approach the first exit time problem is analysed for the process inside the region restricted by the boundaries. The proposed model is also implemented to simulate the effects of a time-dependent therapy. Finally, some numerical results are obtained for the specific case of a parathyroid tumor.
Keywords :
Tumor cells kinetic , diffusion process , Ornstein–Uhlenbeck process , First exit time problem , Gompertz equation
Journal title :
Journal of Theoretical Biology
Journal title :
Journal of Theoretical Biology