Title of article :
Dynamics of epileptic seizures: Evolution, spreading, and suppression
Author/Authors :
Kim، نويسنده , , J.W. and Roberts، نويسنده , , J.A. and Robinson، نويسنده , , P.A.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2009
Abstract :
Dynamical properties of epileptic seizures are investigated using a recent compact continuum model for electric activity of the brain. Large amplitude limit cycles resembling electroencephalograms during epilepsy emerge when the system loses linear stability. Seizures that are confined to an onset area, or spread synchronously to other areas via spatial coupling, are studied and argued to be associated with clinical partial and secondarily generalized seizures, respectively. Suppression of such seizures is also demonstrated, which implies potential for future clinical applications.
Keywords :
Epilepsy , continuum model , Control
Journal title :
Journal of Theoretical Biology
Journal title :
Journal of Theoretical Biology