Title of article
The fixation probability of two competing beneficial mutations
Author/Authors
Yu، نويسنده , , Feng and Etheridge، نويسنده , , Alison، نويسنده ,
Issue Information
دوماهنامه با شماره پیاپی سال 2010
Pages
10
From page
36
To page
45
Abstract
Suppose that a beneficial mutation is undergoing a selective sweep when another beneficial mutation arises at a linked locus. We study the fixation probability of the double mutant, i.e., one (produced by recombination) that carries both mutations. Previous analysis works well for the case where the earlier beneficial mutation confers a greater selective advantage than the later mutation, but not so well in the opposite case. We present an approach to approximating the fixation probability in the case where the later mutation confers a greater selective advantage.
Keywords
Selective sweep , Fixation probability , Interference
Journal title
Theoretical Population Biology
Serial Year
2010
Journal title
Theoretical Population Biology
Record number
1567309
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