• Title of article

    The fixation probability of two competing beneficial mutations

  • Author/Authors

    Yu، نويسنده , , Feng and Etheridge، نويسنده , , Alison، نويسنده ,

  • Issue Information
    دوماهنامه با شماره پیاپی سال 2010
  • Pages
    10
  • From page
    36
  • To page
    45
  • Abstract
    Suppose that a beneficial mutation is undergoing a selective sweep when another beneficial mutation arises at a linked locus. We study the fixation probability of the double mutant, i.e., one (produced by recombination) that carries both mutations. Previous analysis works well for the case where the earlier beneficial mutation confers a greater selective advantage than the later mutation, but not so well in the opposite case. We present an approach to approximating the fixation probability in the case where the later mutation confers a greater selective advantage.
  • Keywords
    Selective sweep , Fixation probability , Interference
  • Journal title
    Theoretical Population Biology
  • Serial Year
    2010
  • Journal title
    Theoretical Population Biology
  • Record number

    1567309