Title of article
Routes from 1,1-cycloalkanedicarboxylic acids to geminal bis(polyfluoromethyl) substituted carbocycles
Author/Authors
Wolniewicz، نويسنده , , Adam and Dmowski، نويسنده , , Wojciech، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2001
Pages
8
From page
95
To page
102
Abstract
1-Fluoroformyl-1-(trifluoromethyl)cycloalkanes (1), prepared by treatment of 1,1-cycloalkane-dicarboxylic acids with SF4, were efficiently reduced to 1-hydroxymethyl-1-(trifluoromethyl)-cycloalkanes (2). Routes for the conversion of alcohols 2 to 1-methyl-1-(trifluoromethyl)cycloalkanes (4), 1-fluoromethyl-1-(trifluoromethyl)cycloalkanes (6) and 1-difluoromethyl-1-(trifluoromethyl)cycloalkanes (8), via iodides 3, triflates 5 and aldehydes 7, respectively, were investigated.
Keywords
1-Formyl-1-(trifluoromethyl)cycloalkanes , Bis(polytrifluoromethyl)cycloalkanes , 1-Hydroxymethyl-1-(trifluoromethyl)cycloalkanes , 1-Fluoroformyl-1-(trifluoromethyl)cycloalkanes
Journal title
Journal of Fluorine Chemistry
Serial Year
2001
Journal title
Journal of Fluorine Chemistry
Record number
1603169
Link To Document