Preparation of δ-fluorinated homoallylic alcohol derivatives via regioselective hydride reduction of allylic alcohol derivatives

δ-Fluoro and δ,δ-difluorohomoallylic alcohol derivatives can be efficiently prepared by LiAlH4 reduction of the δ,δ-difluoroallylic alcohols and the γ-chlorodifluoromethylallylic alcohols, respectively, through regioselective SN2′ reaction, in which the free hydroxyl group is essential for the reaction to proceed.