Title of article :
Synthesis of novel gem-difluorinatedcyclopropane hybrids: Applications for DNA cleavage agents switched by photo irradiation
Author/Authors :
Ninomiya، نويسنده , , Keiko and Tanimoto، نويسنده , , Kunihiko and Ishida، نويسنده , , Nanae and Horii، نويسنده , , Daisuke and Sisido، نويسنده , , Masahiko and Itoh، نويسنده , , Toshiyuki، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2006
Abstract :
A strong DNA cleavage property switched by photo irradiation was found for 9-anthracenecarboxylic acid substituted gem-difluorocyclopropane derivatives; in particular, a clear contrast in the activity was observed between the enantiomers of (S,S)- and (R,R)-3-aminomethyl-2,2-difluorocyclopropylmethyl 9-anthracenecarboxylate.
Keywords :
gem-Difluorinatedcyclopropane–anthracene hybrids , DNA cleavage agents , Photo irradiation , Enantiomer
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry
