Title of article
Synthesis of novel gem-difluorinatedcyclopropane hybrids: Applications for DNA cleavage agents switched by photo irradiation
Author/Authors
Ninomiya، نويسنده , , Keiko and Tanimoto، نويسنده , , Kunihiko and Ishida، نويسنده , , Nanae and Horii، نويسنده , , Daisuke and Sisido، نويسنده , , Masahiko and Itoh، نويسنده , , Toshiyuki، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
6
From page
651
To page
656
Abstract
A strong DNA cleavage property switched by photo irradiation was found for 9-anthracenecarboxylic acid substituted gem-difluorocyclopropane derivatives; in particular, a clear contrast in the activity was observed between the enantiomers of (S,S)- and (R,R)-3-aminomethyl-2,2-difluorocyclopropylmethyl 9-anthracenecarboxylate.
Keywords
gem-Difluorinatedcyclopropane–anthracene hybrids , DNA cleavage agents , Photo irradiation , Enantiomer
Journal title
Journal of Fluorine Chemistry
Serial Year
2006
Journal title
Journal of Fluorine Chemistry
Record number
1603816
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