Title of article
A facile synthetic method for 2-fluoroindolizines from 1-chloro-2,2,2-trifluoroethane (HCFC-133a) and 1,1,1,2-tetrafluoroethane (HFC-134a)
Author/Authors
Wu، نويسنده , , Kai and Chen، نويسنده , , Qing-Yun، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2003
Pages
4
From page
171
To page
174
Abstract
In the presence of KOH and Et3N, pyridinium and isoquinolinium N-ylides generated in situ from their bromides react with 1-chloro-2,2,2-trifluoroethane (HCFC-133a, bp 6 °C) or 1,1,1,2-tetrafluoroethane (HFC-134a, bp −27 °C) to give the corresponding 2-fluoroindolizines via 1,3-dipolar [3+2] cycloaddition at 80–100 °C in DMSO at atmospheric pressure in normal glassware.
Keywords
2-Tetrafluoroethane (HFC-134a) , 2-Fluoroindolizine , 1-Chloro-2 , 3-Dipolar addition , 2-trifluoroethane (HCFC-133a) , 1 , 1 , 2 , 1 , Cycloimmonium N-ylide , 1
Journal title
Journal of Fluorine Chemistry
Serial Year
2003
Journal title
Journal of Fluorine Chemistry
Record number
1607636
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