Title of article :
Reaction of Halothane with sec-butyllithium in the presence of zinc halides—one-pot preparation of chlorodifluorovinylzinc reagent and its derivatization to α-chloro-β,β-difluorostyrene
Author/Authors :
Nishihara، نويسنده , , Masakazu and Nakamura، نويسنده , , Yuki and Maruyama، نويسنده , , Naoki and Sato، نويسنده , , Kazuyuki and Omote، نويسنده , , Masaaki and Ando، نويسنده , , Akira and Kumadaki، نويسنده , , Itsumaro، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2003
Pages :
3
From page :
247
To page :
249
Abstract :
Halothane, 2-bromo-2-chloro-1,1,1-trifluoroethane, reacts with sec-butyllithium in the presence of zinc halides to afford a chlorodifluorovinylzinc reagent. This zinc reagent reacts with aryl halides in the presence of a palladium catalyst to give chlorodifluorostyrene derivatives in moderate to good yields.
Keywords :
HALOTHANE , aryl iodide , Chlorodifluorostyrene , cross-coupling reaction , sec-Butyllithium
Journal title :
Journal of Fluorine Chemistry
Serial Year :
2003
Journal title :
Journal of Fluorine Chemistry
Record number :
1607679
Link To Document :
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