Author/Authors :
Ando، نويسنده , , Akira and Takahashi، نويسنده , , Junko and Nakamura، نويسنده , , Yuki and Maruyama، نويسنده , , Naoki and Nishihara، نويسنده , , Masakazu and Fukushima، نويسنده , , Kaori and Moronaga، نويسنده , , Jin and Inoue، نويسنده , , Mayumi and Sato، نويسنده , , Kazuyuki and Omote، نويسنده , , Masaaki and Kumadaki، نويسنده , , Itsumaro، نويسنده ,
Abstract :
The reaction of halothane, 2-bromo-2-chloro-1,1,1-trifluoroethane (1), with aldehydes and ketones in the presence of bases was found to give 1-alkyl- or 1-aryl-2-bromo-2-chloro-3,3,3-trifluoropropanols (2) or 2-chloro-3,3-difluoro-2-propenols (3) selectively in good to moderate yields depending on the bases and reaction conditions.
Keywords :
HALOTHANE , Butyllithium , fluorine , carbonyl compounds
