Efficient synthesis of new perfluorinated or hybrid amphiphilic surfactants

A very simple pathway for the preparation of amphiphilic analogues of natural bioactive peptidoamines such as carnosine (β-alanylhistidine) or carcinine (β-alanylhistamine), is presented. The strategy makes it possible to synthesise original bialkylchain or trialkylchain perfluorinated surfactants with or without perhydrogenated chains.