Reaction between tert-butyl isocyanide and 1,1,1-trifluoro-4-aryl-butane-2,4-diones: Synthesis of new trifluoromethylated furan derivatives

The 2:1 adducts produced in the reaction between tert-butyl isocyanide and 1,1,1-trifluoro-4-arylbutan-2,4-diones were isolated and characterized as fluorinated aminoketenimines, which undergo enolization-cyclization reactions in boiling chloroform to produce new trifluoromethylated furan derivatives.