Title of article :
The effect of fluoromethyl groups on the diastereoselectivity in the electrophilic alkylation
Author/Authors :
Tamura، نويسنده , , Kenji and Yamazaki، نويسنده , , Takashi and Kitazume، نويسنده , , Tomoya and Kubota، نويسنده , , Toshio، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2005
Abstract :
The effect of fluoromethyl groups on the diastereoselectivity in the electrophilic alkylation is described. In particular, the electrophilic alkylation of enolates with a trifluoromethyl group was proceeded with highly diastereofacial selectivity based on the steric and/or electrostatic effect of substituent with strong electron withdrawing.
Keywords :
diastereoselectivity , Electrophilic alkylation
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry
