Title of article
Synthesis and biological evaluation of γ-fluoro-β,γ-unsaturated acids
Author/Authors
Asakura، نويسنده , , Noriaki and Usuki، نويسنده , , Yoshinosuke and Iio، نويسنده , , Hideo and Tanaka، نويسنده , , Toshio، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
9
From page
800
To page
808
Abstract
Several γ-fluoro-β,γ-unsaturated acids, fluorine-containing analogues of N-acyl glycines, were synthesized via Julia–Lythgoe olefination. The antimicrobial activities of these compounds and synthetic intermediates were evaluated. Analogues with an octyl group showed in vitro antifungal activity agaist Penicillium chrysogenum IFO4626.
Keywords
Julia–Lythgoe olefination , Monofluorinated building block , ?-Fluoro sulfone , antifungal activity
Journal title
Journal of Fluorine Chemistry
Serial Year
2006
Journal title
Journal of Fluorine Chemistry
Record number
1609269
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