Title of article
Simple and convenient synthesis of 3,5-bis-(trifluoromethyl)benzylamine via biomimetic 1,3-proton shift reaction
Author/Authors
Soloshonok، نويسنده , , Vadim A. and Yasumoto، نويسنده , , Manabu، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2006
Pages
5
From page
889
To page
893
Abstract
This paper describes an efficient, practical synthesis of 3,5-bis(trifluoromethyl)benzylamine via biomimetic transamination of 3,5-bis(trifluoromethyl)benzaldehyde with benzylamine. From a synthetic standpoint the reported procedure is highly operationally convenient and scalable as it does not require any chromatographic purification of the intermediate products.
Keywords
3-Proton shift reaction , 1 , Fluorine and compounds , imines , Operationally convenient conditions , Biomimetic reductive methodology
Journal title
Journal of Fluorine Chemistry
Serial Year
2006
Journal title
Journal of Fluorine Chemistry
Record number
1609300
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