Title of article
First enantioselective reductive amination of α-fluoroenones
Author/Authors
Dutheuil، نويسنده , , Guillaume and Bailly، نويسنده , , Laetitia and Couve-Bonnaire، نويسنده , , Samuel and Pannecoucke، نويسنده , , Xavier، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2007
Pages
6
From page
34
To page
39
Abstract
From α-fluoroenones 2, a synthesis of (E) ketone oxime O-alkyl ethers 5 is reported with good to excellent yields. Then the first enantioselective reduction of these ketimines, via oxazaborolidine, is described with moderate to good enantiomeric excesses, leading to valuable chiral fluoroallylic amines 1.
Keywords
Fluoroalkene , Fluoroenone , Ketone oxime ether , oxazaborolidine , Enantioselective reductive amination
Journal title
Journal of Fluorine Chemistry
Serial Year
2007
Journal title
Journal of Fluorine Chemistry
Record number
1609521
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