Title of article
Heck reaction with 3-fluoro-3-buten-2-one
Author/Authors
Patrick ، نويسنده , , Timothy B. and Agboka، نويسنده , , Titus Y. and Gorrell، نويسنده , , Keith، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2008
Pages
3
From page
983
To page
985
Abstract
3-Fluoro-3-buten-2-one (2) is readily prepared from 1-fluoro-1-chloro-2-methoxy-2-methylcyclopropane (1) in 82% yield by heating the cyclopropane in aqueous quinoline solution. Ketone 2 reacts with aryl iodides (3) in a Heck reaction catalyzed by Pd(OAc)2 to give Z-3-fluorobenzalacetones (4) in 36–86% yield.
Keywords
Heck reaction , Fluorovinyl ketone , Fluorobenzalacetone , Palladium coupling
Journal title
Journal of Fluorine Chemistry
Serial Year
2008
Journal title
Journal of Fluorine Chemistry
Record number
1610261
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