Title of article
Synthesis and anti-microbial activity of some new fluorinated 1H-pyrazoles
Author/Authors
Wang، نويسنده , , Dun-Jia and Fan، نويسنده , , Ling-Yun Zheng، نويسنده , , Chun-Yang and Fang، نويسنده , , Zheng-Dong، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2010
Pages
3
From page
584
To page
586
Abstract
Several new trifluoromethyl-1H-pyrazoles were prepared by reaction of hydrazine monohydrate with 1,3-diketones. Their structures were confirmed by elemental analysis, IR, 1H NMR and EI-MS spectroscopy. The anti-microbial activities of the newly synthesized compounds were examined by disc diffusion method against Escherichia coli, Staphylococcus aureus, Pyricularia oryzae and Rhizoctnia solani. All the trifluoromethyl-1H-pyrazoles exhibited a certain degree of anti-bacterial and anti-fungal activities.
Keywords
Trifluoromethyl-1H-pyrazole , Synthesis , 1 , 3-diketones , Anti-microbial activity
Journal title
Journal of Fluorine Chemistry
Serial Year
2010
Journal title
Journal of Fluorine Chemistry
Record number
1610902
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