Title of article
Ionic liquid-aqueous solution ultrasonic-assisted extraction of camptothecin and 10-hydroxycamptothecin from Camptotheca acuminata samara
Author/Authors
Ma، نويسنده , , Chunhui and Wang، نويسنده , , Shu-ya and Yang، نويسنده , , Lei and Zu، نويسنده , , Yuan-gang and Yang، نويسنده , , Feng-jian and Zhao، نويسنده , , Chun-jian and Zhang، نويسنده , , Lin and Zhang، نويسنده , , Zhong-hua، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2012
Pages
6
From page
59
To page
64
Abstract
In this paper, ionic liquid-aqueous solution ultrasonic-assisted extraction (ILUAE) has been successfully applied in extracting camptothecin and 10-hydroxycamptothecin from Camptotheca acuminata samara. The ionic liquids with different cations and anions have been investigated, and 0.75 M 1-octyl-3-methylimidazolium bromide was selected as solvent. In addition, the ultrasonic parameters including ultrasonic power, time for ultrasonic treatment and solid–liquid ratio have been optimized by Response Surface Methodology. Compared with conventional solvent extraction, ILUAE exhibited higher efficiency (camptothecin increased by 13.96% and 10-hydroxycamptothecin increased by 24.04%, respectively) and shorter extraction time (decreased from 6 h to 1.75 h for extracting three times), which indicated that ILUAE was an efficient, rapid and simple sample preparation technique.
Keywords
Camptotheca acuminata , camptothecin , Ionic liquid , ultrasonic-assisted extraction , Response surface methodology , 10-Hydroxycamptothecin
Journal title
Chemical Engineering and Processing: Process Intensification
Serial Year
2012
Journal title
Chemical Engineering and Processing: Process Intensification
Record number
1610950
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