Title of article
Equilibria and kinetics of reactive extraction of pranoprofen enantiomers from organic solution
Author/Authors
Zhang، نويسنده , , Panliang and Cai، نويسنده , , Jian and Tang، نويسنده , , Kewen and Liu، نويسنده , , Yongbing and Liu، نويسنده , , Yuejin and Yan، نويسنده , , Jianhui، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2012
Pages
7
From page
16
To page
22
Abstract
Equilibria and kinetics for reactive extraction of pranoprofen (PRA) enantiomers with methyl-β-cyclodextrin (Me-β-CD) in water as diluent were reported. The theory of extraction accompanied by a chemical reaction has been used to obtain the kinetics. The reactions between Me-β-CD and PRA enantiomers fall in Regime 3. The reactions are first order with respect to PRA and second order with respect to Me-β-CD. The forward rate constants are 2.82 × 10−4 m6/(mol2 s) for S-PRA and 3.53 × 10−4 m6/(mol2 s) for R-PRA, respectively. The developed extraction model is suitable to analyze and evaluate the reactive extraction of PRA enantiomers by Me-β-CD.
Keywords
Reactive extraction , Pranoprofen enantiomers , Kinetics , Equilibria , Chiral separation
Journal title
Chemical Engineering and Processing: Process Intensification
Serial Year
2012
Journal title
Chemical Engineering and Processing: Process Intensification
Record number
1610998
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