Author/Authors :
Martin-Mingot، نويسنده , , Agnès and Compain، نويسنده , , Guillaume and Liu، نويسنده , , Fei and Jouannetaud، نويسنده , , Marie-Paule and Bachmann، نويسنده , , Christian and Frapper، نويسنده , , Gilles and Thibaudeau، نويسنده , , Sébastien، نويسنده ,
Abstract :
The reactivity of aliphatic amides/ketones/imines and nitriles was studied in superacid HF/SbF5 in the presence of CCl4. After the identification of the reaction intermediates by in situ NMR experiments, we propose that the sp3C–H bond functionalization (fluorination) by the superacid system is strongly dependant on the superelectrophilic character of the distonic dicationic intermediates.
Keywords :
Superelectrophile , Functionalization , Superacid , fluorination
