Title of article :
A new synthesis of N-substituted о-trifluoroacetylanilines
Author/Authors :
Shidlovskii، نويسنده , , Alexander F. and Golubev، نويسنده , , Alexander S. and Gusev، نويسنده , , Dmitrii V. and Suponitsky، نويسنده , , Kyrill Yu. and Peregudov، نويسنده , , Alexander S. and Chkanikov، نويسنده , , Nikolai D.، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2012
Abstract :
A method for the synthesis of N-substituted о-trifluoroacetylanilines by the reaction of N-substituted isatoic anhydrides with (trifluoromethyl)trimethylsilane (Ruppert–Prakash reagent) has been developed. This method provides easy access to both N-alkyl-о-trifluoroacetylanilines and N-aryl-о-trifluoroacetylanilines in high yields. Cyclisation of N-aryl-о-trifluoroacetylanilines in trifluoroacetic acid gives 9-trifluoromethylacridines.
Keywords :
Ruppert–Prakash reagent , N-substituted isatoic anhydrides , 9-Trifluoromethylacridines , N-substituted ?-trifluoroacetylanilines
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry
