Title of article
A new synthesis of N-substituted о-trifluoroacetylanilines
Author/Authors
Shidlovskii، نويسنده , , Alexander F. and Golubev، نويسنده , , Alexander S. and Gusev، نويسنده , , Dmitrii V. and Suponitsky، نويسنده , , Kyrill Yu. and Peregudov، نويسنده , , Alexander S. and Chkanikov، نويسنده , , Nikolai D.، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2012
Pages
9
From page
272
To page
280
Abstract
A method for the synthesis of N-substituted о-trifluoroacetylanilines by the reaction of N-substituted isatoic anhydrides with (trifluoromethyl)trimethylsilane (Ruppert–Prakash reagent) has been developed. This method provides easy access to both N-alkyl-о-trifluoroacetylanilines and N-aryl-о-trifluoroacetylanilines in high yields. Cyclisation of N-aryl-о-trifluoroacetylanilines in trifluoroacetic acid gives 9-trifluoromethylacridines.
Keywords
Ruppert–Prakash reagent , N-substituted isatoic anhydrides , 9-Trifluoromethylacridines , N-substituted ?-trifluoroacetylanilines
Journal title
Journal of Fluorine Chemistry
Serial Year
2012
Journal title
Journal of Fluorine Chemistry
Record number
1611896
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