Title of article :
1,3-Dipolar cycloadditions of fluorinated nitrones with thioketones
Author/Authors :
Grzegorz Mloston، نويسنده , , Grzegorz and Obijalska، نويسنده , , Emilia and Celeda، نويسنده , , Ma?gorzata and Mittermeier، نويسنده , , Verena and Linden، نويسنده , , Anthony and Heimgartner، نويسنده , , Heinz، نويسنده ,
Issue Information :
روزنامه با شماره پیاپی سال 2014
Abstract :
Fluorinated nitrones derived from fluoral and difluoroacetaldehyde react with thioketones via [3 + 2] cycloaddition yielding 1,4,2-oxathiazolidines in a regioselective manner. Unexpectedly, cycloaliphatic thioketones react faster than aromatic thioketones. Due to the presence of a fluorinated alkyl group, the cycloadducts display a remarkable stability and do not decompose at room temperature in the crystalline form nor in solution.
Keywords :
Fluorinated heterocycles , Thioketones , Nitrones , 1 , 3-dipolar cycloadditions , 5-Membered heterocycles
Journal title :
Journal of Fluorine Chemistry
Journal title :
Journal of Fluorine Chemistry
