Title of article
Chemical modification of chitosan 11: chitosan–dendrimer hybrid as a tree like molecule
Author/Authors
Sashiwa، نويسنده , , Hitoshi and Shigemasa، نويسنده , , Yoshihiro and Roy، نويسنده , , Rene، نويسنده ,
Issue Information
روزنامه با شماره پیاپی سال 2002
Pages
11
From page
195
To page
205
Abstract
Tetraethylene glycol was modified by two different approaches to synthesize the scaffold of dendrimer. Poly(amido amine) (PAMAM) dendrimers (G=1–3) having tetraethylene glycol spacer were prepared and attached to chitosan by reductive N-alkylation. On chitosan molecules, the degree of substitution of dendrimers was 0.03–0.18. Sialic acid residue bound PAMAM dendrimers of each generation were successfully attached to chitosan.
Keywords
dendrimer , Poly(amido amine) , Sialic acid , Reductive N-alkylation , Chitosan
Journal title
CARBOHYDRATE POLYMERS
Serial Year
2002
Journal title
CARBOHYDRATE POLYMERS
Record number
1612504
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