Fabrication and property of chitosan film carrying ethyl cellulose microspheres

Chitosan (CS) film carrying ethyl cellulose (EC) microspheres (comatrix) is reported in this paper. The properties including interaction, shape change under different condition and its mechanical variety in different ratio of CS to EC microspheres were analyzed by using scanning electron microscope (SEM), X-ray diffraction (XRD), infrared spectra (IR), differential scanning calorimetry (DSC) and mechanical testing. The results indicated that the round EC microspheres dispersed in the CS film, and there was interaction between EC and CS matrix. The comatrix may offer an appropriate property for degradation and drug releasing.