Effect of Aloe vera polysaccharides on immunity and antioxidant activities in oral ulcer animal models

Aloe vera polysaccharides have traditionally been used in Asian cultures as medicinal plants to enhance immunity and reduce oxidative injury. The current investigation was conducted to examine the effects of A. vera polysaccharides on various in vivo parameters of innate immunity and antioxidant enzymes activities in oral ulcer animals. Forty wistar rats were randomly divided into the following 1 control group and 3 experimental groups (each group contained 10 rats). Rats in experimental groups were orally fed by A. vera polysaccharides. Rats in control group were orally fed by same volume of saline. The results showed that A. vera polysaccharides enhanced immunity activity and exerted antioxidant effects compared with vehicle controls. These results demonstrate, for the first time, that A. vera polysaccharides are effective in enhancing innate immunity and suppressing oxidative injury in oral ulcer animals.