Synthesis of polysucrose-based nanoparticles by a one-step method

A set of novel water-soluble polysucrose-based nanoparticles were prepared by a one-step self-assembly method using soluble polysucrose (PS) and acrylic acid (AA) as materials, ceric ammonium nitrate (CAN) as initiator and methylene-bisacrylamide (MBA) as crosslinker. Fourier transform infrared spectroscopy, 13C nuclear magnetic resonance and scanning electron microscopy were utilized to characterize the structure and morphology. The results indicated the dimensions of the nanoparticles increased from 209.7 nm to 293 nm, and the polydispersity index (PDI) decreased, with the increase of AA content from 6.61 to 29.20 mmol/g, while the content of PS (2.5 g), the other components (RMI = 220 and RMC = 35) and experimental conditions were kept constant. The dimensions of nanoparticles increased from 244 nm to 281 nm and the PDI increased with the increase of initiator content from 0.04 to 0.12 mmol/g, while the content of AA (2.1 g), the other components (RSM = 0.25 and RMC = 35) and experimental conditions were kept constant.