Fast ester cleavage of sterically hindered α- and β-aminoesters under non-aqueous conditions. Application to the kinetic resolution of aziridine esters
Author/Authors :
Alezra، نويسنده , , Valérie and Bouchet، نويسنده , , Céline and Micouin، نويسنده , , Laurent and Bonin، نويسنده , , Martine and Husson، نويسنده , , Henri-Philippe Husson، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Pages :
4
From page :
655
To page :
658
Abstract :
Various protected α- and β-aminoesters undergo fast ester cleavage by treatment with t-BuOK in THF. The accelerating effect of a neighboring chelating group was used for the efficient kinetic resolution of non-racemic aziridine esters.
