Title of article :
Total synthesis of lipoxin A4 and lipoxin B4 from butadiene
Author/Authors :
Rodr??guez، نويسنده , , A and Nomen، نويسنده , , M and Spur، نويسنده , , B.W and Godfroid، نويسنده , , J.J. and Lee، نويسنده , , T.H، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
The total synthesis of LXA4 and LXB4 has been achieved starting from butadiene via palladium catalyzed telomerization. Sharpless catalytic AE and C-2 inversion of the 2(S),3(S)-epoxy alcohols, using Myers CO2/Cs2CO3 procedure, generated the asymmetric centers. The flexibility of the strategy allows an easy access to the linear eicosanoids.
Keywords :
palladium catalyst , Eicosanoids , inversion reaction , Katsuki–Sharpless reaction
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
