Title of article
Efficient convergent synthesis of a trans-fused 6-6-6-6-membered tetracyclic ether ring system
Author/Authors
Matsuo، نويسنده , , Goh and Hinou، نويسنده , , Hiroshi and Koshino، نويسنده , , Hiroyuki and Suenaga، نويسنده , , Toshiro and Nakata، نويسنده , , Tadashi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
903
To page
906
Abstract
A very efficient convergent strategy for the construction of the trans-fused 6-6-6-6-membered tetracyclic ether ring system was developed based on the acetylide-triflate coupling of two tetrahydropyrans, oxidation of the alkyne group to an α-diketone, double cyclization to 6,6,6,6-membered tetracyclic diacetal, and stereoselective reduction of the diacetal with Et3SiH–TMSOTf.
Keywords
Alkynes , coupling reactions , acetals , tetrahydropyrans , polyethers , Reduction
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1636310
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