Title of article
meta-Aminoazobenzene as a thermo-insensitive photo-regulator of DNA-duplex formation
Author/Authors
Asanuma، نويسنده , , Hiroyuki and Liang، نويسنده , , Xingguo and Komiyama، نويسنده , , Makoto، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
1055
To page
1058
Abstract
meta-Aminoazobenzene has been introduced in the side chain of oligonucleotides as a photo-responsive molecule. Compared with the para-aminoazobenzene which was previously used, the thermal cis→trans isomerization was much slower: the half-lives of the cis-isomers of m- and p-aminoazobenzene were 13.2 h and 20 min at 50°C, respectively. By using the present oligonucleotides, duplex formation and dissociation was efficiently regulated on photo-irradiation without being disturbed by the thermal isomerization.
Keywords
photochemistry , Azo Compounds , azo , Isomerization , Phosphoramidites
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1636409
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