Title of article :
A practical and efficient intramolecular Michael addition of ureas to α,β-unsaturated esters
Author/Authors :
Xin، نويسنده , , Zhili and Pei، نويسنده , , Zhonghua and von Geldem، نويسنده , , Tom and Jirousek، نويسنده , , Michael، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
A mild and efficient method is described for the synthesis of dihydroquinazoline derivatives via intramolecular hetero-Michael addition of ureas to ortho-substituted α,β-unsaturated esters in the presence of NaOH in THF with high chemical yield.
Keywords :
Michael addition , Ureas , dihydroquinazolines , cyclization
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters