Title of article
Zinc triflate–bis-oxazoline complexes as chiral catalysts: enantioselective reduction of α-alkoxy-ketones with catecholborane
Author/Authors
Bandini، نويسنده , , Marco and Cozzi، نويسنده , , Pier Giorgio and de Angelis، نويسنده , , Meri and Umani-Ronchi *، نويسنده , , Achille، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
5
From page
1601
To page
1605
Abstract
A new methodology for the catalytic enantioselective reduction of α-alkoxy-ketones is described. The procedure employes Zn(OTf)2–bis-oxazoline complexes (8–10 mol%) as catalysts and catecholborane as the reducing agent. The reaction, carried out in CH2Cl2 at 0°C, affords the α-alkoxy-alcohols in high yields and with good enantioselectivity.
Keywords
Asymmetric reactions , Catalysis , ketones , Reduction
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1636537
Link To Document