Title of article :
A new method of forming resin bound thioesters and their use as ‘traceless’ linkers in solid phase synthesis
Author/Authors :
May، نويسنده , , Peter J and Bradley، نويسنده , , Mark and Harrowven *، نويسنده , , David C and Pallin، نويسنده , , David، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
Resin bound thioesters can be prepared by heating thioamides in aqueous DMF with Merrifield resin in the presence of sodium iodide. These thioamides can be cleaved to give alcohols, ketones and lactones by a variety of methods.
Keywords :
Combinatorial chemistry , Lactones , Solid phase synthesis , Thioamide , thioester
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
