Author/Authors :
Ishihara، نويسنده , , Jun and Hagihara، نويسنده , , Koji and Chiba، نويسنده , , Hiroyuki and Ito، نويسنده , , Kouichi and Yanagisawa، نويسنده , , Yumiko and Totani، نويسنده , , Kiichiro and Tadano، نويسنده , , Kin-ichi، نويسنده ,
Abstract :
A highly functionalized cyclopentene carboxylic acid derivative, as an advanced synthetic intermediate of viridenomycin, was synthesized. The synthesis commenced with the previously reported highly functionalized tetrahydrofuran derivative prepared from d-glucose. The stereochemical confirmation of the present final compound was conducted by comparison with a compound synthesized very recently by the Meyers group.
Keywords :
Antitumor compounds , cyclopentenes , cyclization , regiocontrol , Polyenes
