• Title of article

    Direct conversion of Fmoc-protected amines into O-alkyl carbamates by the Mitsunobu reaction: a practical strategy for the solid-phase synthesis of carbamates

  • Author/Authors

    Zaragoza، نويسنده , , Florencio and Stephensen، نويسنده , , Henrik، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2000
  • Pages
    3
  • From page
    2015
  • To page
    2017
  • Abstract
    Support-bound, Fmoc-protected amines react with aliphatic alcohols in the presence of ADDP, PBu3, and DIPEA to yield O-alkyl carbamates. The reaction presumably proceeds via O-alkylation of an intermediate carbamate anion.
  • Keywords
    solid-phase synthesis , amino acids and derivatives , Carbamates , Mitsunobu reactions
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2000
  • Journal title
    Tetrahedron Letters
  • Record number

    1636628