Title of article
Direct conversion of Fmoc-protected amines into O-alkyl carbamates by the Mitsunobu reaction: a practical strategy for the solid-phase synthesis of carbamates
Author/Authors
Zaragoza، نويسنده , , Florencio and Stephensen، نويسنده , , Henrik، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
3
From page
2015
To page
2017
Abstract
Support-bound, Fmoc-protected amines react with aliphatic alcohols in the presence of ADDP, PBu3, and DIPEA to yield O-alkyl carbamates. The reaction presumably proceeds via O-alkylation of an intermediate carbamate anion.
Keywords
solid-phase synthesis , amino acids and derivatives , Carbamates , Mitsunobu reactions
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1636628
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