Title of article
Enantiomeric deoxy-l-nucleotides stabilize a Z-forming DNA decanucleotide
Author/Authors
Sophie Vichier-Guerre، نويسنده , , Sophie and Santamaria، نويسنده , , Fanny and Rayner، نويسنده , , Bernard، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2000
Pages
4
From page
2101
To page
2104
Abstract
Two contiguous pairs of enantiomeric 2′-deoxy-l-ribonucleotides have been incorporated in a 5-methyl-CG alternating decadeoxyribonucleotide duplex. Data from circular dichroism and UV melting experiments indicate that the two base-pair long enantio-domain within the duplex was able to stabilize a Z-DNA-like conformation.
Keywords
Conformation , Nucleic acids , circular dichroism , enantiomeric nucleotides
Journal title
Tetrahedron Letters
Serial Year
2000
Journal title
Tetrahedron Letters
Record number
1636648
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