Title of article :
Concise asymmetric synthesis of dysidiolide
Author/Authors :
Takahashi، نويسنده , , Masato and Dodo، نويسنده , , Kosuke and Hashimoto، نويسنده , , Yuichi and Shirai، نويسنده , , Ryuichi، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2000
Abstract :
The cdc25A protein phosphatase inhibitor dysidiolide (1) has been synthesized via intermolecular Diels–Alder reaction of the triene 4 with crotonaldehyde and construction of a quaternary carbon center by methylation of the exocyclic enolate.
Keywords :
terpene , Diels–Alder reaction , asymmetric synthesis , Alkylation , Anti-cancer agent
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
